BA, the congenital absence or destruction of intra- or extra-hepatic biliary system, affects about 5 - 10/100 000 live births. End stage liver cirrhosis developed in some BA patients later in life. As a result of liver cirrhosis, regenerative nodules may develop in cirrhotic liver including a specific type termed MRN. The clinical significance and pathological features of MRN have been discussed in some articles. However, the image features of MRN and how to differentiate them from HCC have yet to be elucidated. A research article to be published on July 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Yu-Fan Cheng from Chang-Gung memorial hospital- Kaohsiung medical center found that MRN developed in about 5% BA patients and there was no malignant change within them...
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