Dimebon Improves Symptoms of Alzheimer's Over 12 Months (Interview with Rachelle Doody, MD, PhD)

The Russian antihistamine Dimebon improves mild-to-moderate symptoms of Alzheimer's disease over 12 months, according to a controlled trial published in this week's Dementia Special Edition of The Lancet. Here are some recommendations for the early detection of dementia, from the American Academy of Neurology: • Patients with mild cognitive impairment should be recognized and monitored for cognitive and functional decline due to their increased risk for subsequent dementia. • General cognitive screening instruments (e.g., Mini-Mental State Examination) should be considered for the detection of dementia in individuals with suspected cognitive impairment. • Brief cognitive assessment instruments that focus on limited aspects of cognitive function (i.e., Clock Drawing Test, Time and Change Test) may be considered when screening... [read full story]