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Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment.

Departments of Surgery, Pathology, Pharmacology and Cancer Biology, and Medicine, and Institute for Genome Sciences and Policy, Duke University. Malignant transformation in melanoma is characterized by a phenotype "switch" from E- to N-cadherin, which is associated with increased motility and... [read full story]                    

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