The transcription factor Nfix is essential for normal brain development.

biowizard.com     May 17, 2008          

ABSTRACT: BACKGROUND: The Nuclear Factor I (NFI) multi-gene family encodes site-specific transcription factors essential for the development of a number of organ systems. We showed previously that Nfia-deficient mice exhibit agenesis of the corpus callosum and other forebrain defects,... [read full story]                

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