Prostate Cancer: Research conducted at University of Tampere has provided new information about...

Research conducted at University of Tampere has provided new information about prostate cancer A new study, 'C-reactive protein haplotype is associated with high PSA as a marker of metastatic prostate cancer but not with overall , has not been evaluated thoroughly in prostate cancer (PC)." "In this study of 739 Finnish patients with PC and 760 healthy men, we evaluated the associations of CRP genotypes and haplotypes with total PC risk and PC progression, using prostate-specific antigen (PSA) as a marker of metastatic disease. Although the haplotype frequencies were similar in patients and controls, an association between haplotype ACCCA and patients' PSA levels was found. The carriers more often had a high PSA than non-carriers (p=0.0002) and the SNP rs2794521 A-allele and rs1800947 C-allele carriers had a higher PSA than... [read full story]                    

powered by