Jennerex Completes the Treatment of First Patient Cohort in Phase 1 Trial With Intravenous...

Posted on: Wednesday, 15 October 2008, 12:00 CDT SAN FRANCISCO, Oct. 15 /PRNewswire/ -- Jennerex, Inc. (San Francisco, CA and Ottawa, Canada) today announced the completion of treatment for the first patient cohort in the Phase 1 cancer clinical trial of its targeted poxvirus JX-594, delivered by intravenous (IV) infusion. No significant toxicities were reported, and treatment was well-tolerated. The Phase 1 IV trial involves treatment of patients with advanced, metastatic solid tumors refractory to standard therapy. Patients receive treatment at one of five dose levels in a sequential dose-escalating design; the first cohort has now been treated safely. Once the maximum tolerated dose is defined, an additional three to six patients will be enrolled at that dose level. The trial is being conducted initially at clinical sites... [read full story]