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Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment.

May 19, 2008
Story Timeline:  197 days

Departments of Surgery, Pathology, Pharmacology and Cancer Biology, and Medicine, and Institute for Genome Sciences and Policy, Duke University. Malignant transformation in melanoma is characterized by a phenotype "switch" from E- to N-cadherin, which is associated with increased motility and... [read full story]                    

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